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Cation Permeability of Voltage-Gated Hair Cell Ca(2+) Channels of the Vertebrate Labyrinth

Some hearing, vestibular, and vision disorders are imputable to voltage-gated Ca(2+) channels of the sensory cells. These channels convey a large Ca(2+) influx despite extracellular Na(+) being 70-fold more concentrated than Ca(2+); such high selectivity is lost in low Ca(2+), and Na(+) can permeate...

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Detalles Bibliográficos
Autores principales: Martini, Marta, Rispoli, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998708/
https://www.ncbi.nlm.nih.gov/pubmed/35409146
http://dx.doi.org/10.3390/ijms23073786