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CRISPR/Cas9-Mediated Knockout of miR-130b Affects Mono- and Polyunsaturated Fatty Acid Content via PPARG-PGC1α Axis in Goat Mammary Epithelial Cells

MicroRNA (miRNA)-130b, as a regulator of lipid metabolism in adipose and mammary gland tissues, is actively involved in lipogenesis, but its endogenous role in fatty acid synthesis remains unclear. Here, we aimed to explore the function and underlying mechanism of miR-130b in fatty acid synthesis us...

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Detalles Bibliográficos
Autores principales: Huang, Lian, Luo, Jun, Song, Ning, Gao, Wenchang, Zhu, Lu, Yao, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998713/
https://www.ncbi.nlm.nih.gov/pubmed/35409000
http://dx.doi.org/10.3390/ijms23073640