Dexamethasone Attenuates the Expression of MMP-13 in Chondrocytes through MKP-1

Mitogen-activated protein kinase phosphatase-1 (MKP-1) is upregulated in inflammation and reduces the activity of proinflammatory mitogen-activated protein kinases (MAP kinases) by dephosphorylation. MAP kinases are intracellular signaling pathways that mediate the cellular effects of proinflammator...

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Detalles Bibliográficos
Autores principales: Lehtola, Tiina, Nummenmaa, Elina, Tuure, Lauri, Hämäläinen, Mari, Nieminen, Riina M., Moilanen, Teemu, Pemmari, Antti, Moilanen, Eeva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998740/
https://www.ncbi.nlm.nih.gov/pubmed/35409238
http://dx.doi.org/10.3390/ijms23073880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998740/
https://www.ncbi.nlm.nih.gov/pubmed/35409238
http://dx.doi.org/10.3390/ijms23073880

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