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Dexamethasone Attenuates the Expression of MMP-13 in Chondrocytes through MKP-1
Mitogen-activated protein kinase phosphatase-1 (MKP-1) is upregulated in inflammation and reduces the activity of proinflammatory mitogen-activated protein kinases (MAP kinases) by dephosphorylation. MAP kinases are intracellular signaling pathways that mediate the cellular effects of proinflammator...
Autores principales: | Lehtola, Tiina, Nummenmaa, Elina, Tuure, Lauri, Hämäläinen, Mari, Nieminen, Riina M., Moilanen, Teemu, Pemmari, Antti, Moilanen, Eeva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998740/ https://www.ncbi.nlm.nih.gov/pubmed/35409238 http://dx.doi.org/10.3390/ijms23073880 |
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