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Comparative Analysis of Transcriptional Responses to Genotoxic and Non-Genotoxic Agents in the Blood Cell Model TK6 and the Liver Model HepaRG

Transcript signatures are a promising approach to identify and classify genotoxic and non-genotoxic compounds and are of interest as biomarkers or for future regulatory application. Not much data, however, is yet available about the concordance of transcriptional responses in different cell types or...

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Detalles Bibliográficos
Autores principales: Kreuzer, Katrin, Sprenger, Heike, Braeuning, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998745/
https://www.ncbi.nlm.nih.gov/pubmed/35408779
http://dx.doi.org/10.3390/ijms23073420