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L-plastin enhances NLRP3 inflammasome assembly and bleomycin-induced lung fibrosis
Macrophage adhesion and stretching have been shown to induce interleukin (IL)-1β production, but the mechanism of this mechanotransduction remains unclear. Here we specify the molecular link between mechanical tension on tissue-resident macrophages and activation of the NLRP3 inflammasome, which gov...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998782/ https://www.ncbi.nlm.nih.gov/pubmed/35294888 http://dx.doi.org/10.1016/j.celrep.2022.110507 |