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GABA(A) Receptor Autoantibodies Decrease GABAergic Synaptic Transmission in the Hippocampal CA3 Network

Autoimmune encephalitis associated with antibodies (Abs) against α1, β3, and γ2 subunits of γ-aminobutyric acid receptor A (GABA(A)R) represents a severe form of encephalitis with refractory seizures and status epilepticus. Reduction in inhibitory GABAergic synaptic activity is linked to dysfunction...

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Detalles Bibliográficos
Autores principales: Menke, Amélie F., Ismail, Fatme Seval, Dornmair, Klaus, Cerina, Manuela, Meuth, Sven G., Melzer, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998798/
https://www.ncbi.nlm.nih.gov/pubmed/35409067
http://dx.doi.org/10.3390/ijms23073707