FTO m6A Demethylase in Obesity and Cancer: Implications and Underlying Molecular Mechanisms

Fat mass and obesity-associated protein (FTO) is the first reported RNA N6-methyladenosine (m6A) demethylase in eukaryotic cells. m6A is considered as the most abundant mRNA internal modification, which modulates several cellular processes including alternative splicing, stability, and expression. G...

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Detalles Bibliográficos
Autores principales: Azzam, Sarah Kassem, Alsafar, Habiba, Sajini, Abdulrahim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998816/
https://www.ncbi.nlm.nih.gov/pubmed/35409166
http://dx.doi.org/10.3390/ijms23073800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998816/
https://www.ncbi.nlm.nih.gov/pubmed/35409166
http://dx.doi.org/10.3390/ijms23073800

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