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FTO m6A Demethylase in Obesity and Cancer: Implications and Underlying Molecular Mechanisms
Fat mass and obesity-associated protein (FTO) is the first reported RNA N6-methyladenosine (m6A) demethylase in eukaryotic cells. m6A is considered as the most abundant mRNA internal modification, which modulates several cellular processes including alternative splicing, stability, and expression. G...
Autores principales: | Azzam, Sarah Kassem, Alsafar, Habiba, Sajini, Abdulrahim A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998816/ https://www.ncbi.nlm.nih.gov/pubmed/35409166 http://dx.doi.org/10.3390/ijms23073800 |
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