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Anticoagulant Oligonucleotide–Peptide Conjugates: Identification of Thrombin Aptamer Conjugates with Improved Characteristics

Oligonucleotide–peptide conjugates (OPCs) are a promising class of biologically active compounds with proven potential for improving nucleic acid therapeutics. OPCs are commonly recognized as an efficient instrument to enhance the cellular delivery of therapeutic nucleic acids. In addition to this a...

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Detalles Bibliográficos
Autores principales: Tsvetkov, Vladimir B., Varizhuk, Irina V., Kurochkin, Nikolay N., Surzhikov, Sergei A., Smirnov, Igor P., Stomakhin, Andrey A., Kolganova, Natalia A., Timofeev, Edward N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998821/
https://www.ncbi.nlm.nih.gov/pubmed/35409180
http://dx.doi.org/10.3390/ijms23073820