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SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma?

Targeting molecular alterations as an effective treatment for isocitrate dehydrogenase-wildtype glioblastoma (GBM) patients has not yet been established. Sterol-O-Acyl Transferase 1 (SOAT1), a key enzyme in the conversion of endoplasmic reticulum cholesterol to esters for storage in lipid droplets (...

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Detalles Bibliográficos
Autores principales: Löhr, Mario, Härtig, Wolfgang, Schulze, Almut, Kroiß, Matthias, Sbiera, Silviu, Lapa, Constantin, Mages, Bianca, Strobel, Sabrina, Hundt, Jennifer Elisabeth, Bohnert, Simone, Kircher, Stefan, Janaki-Raman, Sudha, Monoranu, Camelia-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998855/
https://www.ncbi.nlm.nih.gov/pubmed/35409086
http://dx.doi.org/10.3390/ijms23073726