LINE-1 Cargo and Reverse Transcriptase Activity Profiles in Extracellular Vesicles from Lung Cancer Cells and Human Plasma

Long Interspersed Element-1 (LINE-1) is an oncogenic human retrotransposon that ‘copies and pastes’ DNA into new locations via reverse transcription. Given that enzymatically active LINE-1 can be exported in extracellular vesicles (EVs), and that LINE-1 mRNA and its two encoded proteins, ORF1p and O...

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Detalles Bibliográficos
Autores principales: Bowers, Emma C., Motta, Alexandre, Knox, Ken, McKay, Brian S., Ramos, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998977/
https://www.ncbi.nlm.nih.gov/pubmed/35408821
http://dx.doi.org/10.3390/ijms23073461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998977/
https://www.ncbi.nlm.nih.gov/pubmed/35408821
http://dx.doi.org/10.3390/ijms23073461

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