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Cyclin-Dependent Kinase Synthetic Lethality Partners in DNA Damage Response

Cyclin-dependent kinases (CDKs) are pivotal mediators and effectors of the DNA damage response (DDR) that regulate both the pathway components and proteins involved in repair processes. Synthetic lethality (SL) describes a situation in which two genes are linked in such a way that the lack of functi...

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Detalles Bibliográficos
Autores principales: Kciuk, Mateusz, Gielecińska, Adrianna, Mujwar, Somdutt, Mojzych, Mariusz, Kontek, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998982/
https://www.ncbi.nlm.nih.gov/pubmed/35408915
http://dx.doi.org/10.3390/ijms23073555