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Cyclin-Dependent Kinase Synthetic Lethality Partners in DNA Damage Response
Cyclin-dependent kinases (CDKs) are pivotal mediators and effectors of the DNA damage response (DDR) that regulate both the pathway components and proteins involved in repair processes. Synthetic lethality (SL) describes a situation in which two genes are linked in such a way that the lack of functi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998982/ https://www.ncbi.nlm.nih.gov/pubmed/35408915 http://dx.doi.org/10.3390/ijms23073555 |