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ENPP2 Promoter Methylation Correlates with Decreased Gene Expression in Breast Cancer: Implementation as a Liquid Biopsy Biomarker

Autotaxin (ATX), encoded by the ctonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2) gene, is a key enzyme in lysophosphatidic acid (LPA) synthesis. We have recently described ENPP2 methylation profiles in health and multiple malignancies and demonstrated correlation to its aberrant expression....

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Detalles Bibliográficos
Autores principales: Panagopoulou, Maria, Drosouni, Andrianna, Fanidis, Dionysiοs, Karaglani, Makrina, Balgkouranidou, Ioanna, Xenidis, Nikolaos, Aidinis, Vassilis, Chatzaki, Ekaterini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998992/
https://www.ncbi.nlm.nih.gov/pubmed/35409077
http://dx.doi.org/10.3390/ijms23073717