The Path to Therapeutic Furin Inhibitors: From Yeast Pheromones to SARS-CoV-2

The spurious acquisition and optimization of a furin cleavage site in the SARS-CoV-2 spike protein is associated with increased viral transmission and disease, and has generated intense interest in the development and application of therapeutic furin inhibitors to thwart the COVID-19 pandemic. This...

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Detalles Bibliográficos
Autores principales: Thomas, Gary, Couture, Frédéric, Kwiatkowska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999023/
https://www.ncbi.nlm.nih.gov/pubmed/35408793
http://dx.doi.org/10.3390/ijms23073435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999023/
https://www.ncbi.nlm.nih.gov/pubmed/35408793
http://dx.doi.org/10.3390/ijms23073435

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