IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis

Interleukin-11 (IL11) is important for fibrosis and inflammation, but its role in the pancreas is unclear. In pancreatitis, fibrosis, inflammation and organ dysfunction are associated with pancreatic stellate cell (PSC)-to-myofibroblast transformation. Here, we show that IL11 stimulation of PSCs, wh...

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Detalles Bibliográficos
Autores principales: Ng, Benjamin, Viswanathan, Sivakumar, Widjaja, Anissa A., Lim, Wei-Wen, Shekeran, Shamini G., Goh, Joyce Wei Ting, Tan, Jessie, Kuthubudeen, Fathima, Lim, Sze Yun, Xie, Chen, Schafer, Sebastian, Adami, Eleonora, Cook, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999048/
https://www.ncbi.nlm.nih.gov/pubmed/35408908
http://dx.doi.org/10.3390/ijms23073549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999048/
https://www.ncbi.nlm.nih.gov/pubmed/35408908
http://dx.doi.org/10.3390/ijms23073549

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