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Context Dependent Sulf1/Sulf2 Functional Divergence in Endothelial Cell Activity

Signalling activities are tightly regulated to control cellular responses. Heparan sulfate proteoglycans (HSPGs) at the cell membrane and extracellular matrix regulate ligand availability and interaction with a range of key receptors. SULF1 and SULF2 enzymes modify HSPG sulfation by removing 6-O sul...

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Detalles Bibliográficos
Autores principales: Justo, Tiago, Smart, Nicola, Dhoot, Gurtej K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999074/
https://www.ncbi.nlm.nih.gov/pubmed/35409127
http://dx.doi.org/10.3390/ijms23073769