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Sex Differences in Metabolic Indices and Chronic Neuroinflammation in Response to Prolonged High-Fat Diet in ApoE4 Knock-In Mice

Late-onset Alzheimer’s disease (LOAD) likely results from combinations of risk factors that include both genetic predisposition and modifiable lifestyle factors. The E4 allele of apolipoprotein E (ApoE) is the most significant genetic risk factor for LOAD. A Western-pattern diet (WD) has been shown...

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Detalles Bibliográficos
Autores principales: Mattar, Jennifer M., Majchrzak, Mark, Iannucci, Jaclyn, Bartman, Sydney, Robinson, John K., Grammas, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999114/
https://www.ncbi.nlm.nih.gov/pubmed/35409283
http://dx.doi.org/10.3390/ijms23073921