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Sex Differences in Metabolic Indices and Chronic Neuroinflammation in Response to Prolonged High-Fat Diet in ApoE4 Knock-In Mice
Late-onset Alzheimer’s disease (LOAD) likely results from combinations of risk factors that include both genetic predisposition and modifiable lifestyle factors. The E4 allele of apolipoprotein E (ApoE) is the most significant genetic risk factor for LOAD. A Western-pattern diet (WD) has been shown...
Autores principales: | Mattar, Jennifer M., Majchrzak, Mark, Iannucci, Jaclyn, Bartman, Sydney, Robinson, John K., Grammas, Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999114/ https://www.ncbi.nlm.nih.gov/pubmed/35409283 http://dx.doi.org/10.3390/ijms23073921 |
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