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Sprague Dawley Rats Show More Severe Bone Loss, Osteophytosis and Inflammation Compared to Wistar Han Rats in a High-Fat, High-Sucrose Diet Model of Joint Damage

In animal models, joint degeneration observed in response to obesogenic diet varies in nature and severity. In this study, we compare joint damage in Sprague Dawley and Wistar-Han rats in response to a high-fat, high-sucrose (HFS) diet groove model of osteoarthritis (OA). Wistar Han (n = 5) and Spra...

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Detalles Bibliográficos
Autores principales: Warmink, Kelly, Rios, Jaqueline L., van Valkengoed, Devin R., Korthagen, Nicoline M., Weinans, Harrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999132/
https://www.ncbi.nlm.nih.gov/pubmed/35409085
http://dx.doi.org/10.3390/ijms23073725