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Antinociceptive and Antiallodynic Activity of Some 3-(3-Methylthiophen-2-yl)pyrrolidine-2,5-dione Derivatives in Mouse Models of Tonic and Neuropathic Pain

Antiseizure drugs (ASDs) are commonly used to treat a wide range of nonepileptic conditions, including pain. In this context, the analgesic effect of four pyrrolidine-2,5-dione derivatives (compounds 3, 4, 6, and 9), with previously confirmed anticonvulsant and preliminary antinociceptive activity,...

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Detalles Bibliográficos
Autores principales: Dziubina, Anna, Rapacz, Anna, Czopek, Anna, Góra, Małgorzata, Obniska, Jolanta, Kamiński, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999233/
https://www.ncbi.nlm.nih.gov/pubmed/35409413
http://dx.doi.org/10.3390/ijms23074057