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Protease inhibitor Camostat Mesyalte blocks wild type SARS-CoV-2 and D614G viral entry in human engineered miniature lungs

The catastrophic global effects of the SARS-CoV-2 pandemic highlight the need to develop novel therapeutics strategies to prevent and treat viral infections of the respiratory tract. To enable this work, we need scalable, affordable, and physiologically relevant models of the human lung, the primary...

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Detalles Bibliográficos
Autores principales: Wu, Tong, Rabi, Seyed A., Michaud, William A., Becerra, David, Gilpin, Sarah E., Mino-Kenudson, Mari, Ott, Harald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999341/
https://www.ncbi.nlm.nih.gov/pubmed/35533440
http://dx.doi.org/10.1016/j.biomaterials.2022.121509