Comparison between Nanoparticle Encapsulation and Surface Loading for Lysosomal Enzyme Replacement Therapy

Poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) enhance the delivery of therapeutic enzymes for replacement therapy of lysosomal storage disorders. Previous studies examined NPs encapsulating or coated with enzymes, but these formulations have never been compared. We examined this using hyalur...

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Detalles Bibliográficos
Autores principales: Muntimadugu, Eameema, Silva-Abreu, Marcelle, Vives, Guillem, Loeck, Maximilian, Pham, Vy, del Moral, Maria, Solomon, Melani, Muro, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999373/
https://www.ncbi.nlm.nih.gov/pubmed/35409394
http://dx.doi.org/10.3390/ijms23074034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999373/
https://www.ncbi.nlm.nih.gov/pubmed/35409394
http://dx.doi.org/10.3390/ijms23074034

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