Synthesis and Biological Evaluation of Novel Bufalin Derivatives

Bufalin and other cardiac steroids (CS) have been used for centuries for the treatment of congestive heart failure, arrhythmias, and other maladies. However, toxicity and the small therapeutic window of this family of steroids limit their use. Therefore, attempts to synthesize a potent, but less tox...

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Detalles Bibliográficos
Autores principales: Sampath, VishnuPriya, Horesh, Noa, Sasi, Ben, Zannadeh, Hiba, Pogodin, Ilana, Singh, Shiv Vardan, Deutsch, Joseph, Lichtstein, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999407/
https://www.ncbi.nlm.nih.gov/pubmed/35409366
http://dx.doi.org/10.3390/ijms23074007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999407/
https://www.ncbi.nlm.nih.gov/pubmed/35409366
http://dx.doi.org/10.3390/ijms23074007

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