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Required Elements in tRNA for Methylation by the Eukaryotic tRNA (Guanine-N(2)-) Methyltransferase (Trm11-Trm112 Complex)

The Saccharomyces cerevisiae Trm11 and Trm112 complex (Trm11-Trm112) methylates the 2-amino group of guanosine at position 10 in tRNA and forms N(2)-methylguanosine. To determine the elements required in tRNA for methylation by Trm11-Trm112, we prepared 60 tRNA transcript variants and tested them fo...

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Detalles Bibliográficos
Autores principales: Nishida, Yu, Ohmori, Shiho, Kakizono, Risa, Kawai, Kunpei, Namba, Miyu, Okada, Kazuki, Yamagami, Ryota, Hirata, Akira, Hori, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999500/
https://www.ncbi.nlm.nih.gov/pubmed/35409407
http://dx.doi.org/10.3390/ijms23074046