Imetelstat Induces Leukemia Stem Cell Death in Pediatric Acute Myeloid Leukemia Patient-Derived Xenografts

SIMPLE SUMMARY: About 20% of children with acute myeloid leukemia (AML) experience refractory disease or relapse, despite receiving intensive therapy. Leukemia stem cells (LSC) have the ability to evade chemotherapy and propagate the disease leading to chemoresistance and relapse. Therefore, treatme...

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Detalles Bibliográficos
Autores principales: Barwe, Sonali P., Huang, Fei, Kolb, Edward Anders, Gopalakrishnapillai, Anilkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999576/
https://www.ncbi.nlm.nih.gov/pubmed/35407531
http://dx.doi.org/10.3390/jcm11071923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999576/
https://www.ncbi.nlm.nih.gov/pubmed/35407531
http://dx.doi.org/10.3390/jcm11071923

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