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The Effects of TNF-α Inhibition on the Metabolism of Cartilage: Relationship between KS, HA, HAPLN1 and ADAMTS4, ADAMTS5, TOS and TGF-β1 Plasma Concentrations in Patients with Juvenile Idiopathic Arthritis

We assessed the effect of 24-month anti-tumor necrosis factor alpha (TNF-α) treatment on the remodeling of the cartilage extracellular matrix (ECM) in patients with juvenile idiopathic arthritis (JIA). Methods: Quantitative evaluation of keratan sulfate (KS), hyaluronic acid (HA), hyaluronan and pro...

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Detalles Bibliográficos
Autores principales: Kuźnik-Trocha, Kornelia, Winsz-Szczotka, Katarzyna, Lachór-Motyka, Iwona, Dąbkowska, Klaudia, Wojdas, Magdalena, Olczyk, Krystyna, Komosińska-Vassev, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999578/
https://www.ncbi.nlm.nih.gov/pubmed/35407621
http://dx.doi.org/10.3390/jcm11072013