Hepatic PTEN Signaling Regulates Systemic Metabolic Homeostasis through Hepatokines-Mediated Liver-to-Peripheral Organs Crosstalk

Liver-derived circulating factors deeply affect the metabolism of distal organs. Herein, we took advantage of the hepatocyte-specific PTEN knockout mice (LPTENKO), a model of hepatic steatosis associated with increased muscle insulin sensitivity and decreased adiposity, to identify potential secrete...

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Detalles Bibliográficos
Autores principales: Berthou, Flavien, Sobolewski, Cyril, Abegg, Daniel, Fournier, Margot, Maeder, Christine, Dolicka, Dobrochna, Correia de Sousa, Marta, Adibekian, Alexander, Foti, Michelangelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999584/
https://www.ncbi.nlm.nih.gov/pubmed/35409319
http://dx.doi.org/10.3390/ijms23073959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999584/
https://www.ncbi.nlm.nih.gov/pubmed/35409319
http://dx.doi.org/10.3390/ijms23073959

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