Dual Inhibition of H3K9me2 and H3K27me3 Promotes Tumor Cell Senescence without Triggering the Secretion of SASP

Chemotherapy remains the most common cancer treatment. Although chemotherapeutic drugs induce tumor cell senescence, they are often associated with post-therapy tumor recurrence by inducing the senescence-associated secretory phenotype (SASP). Therefore, it is important to identify effective strateg...

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Detalles Bibliográficos
Autores principales: Zhang, Na, Shang, Mengjie, Li, Hongxin, Wu, Lan, Dong, Meichen, Huang, Baiqu, Lu, Jun, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999616/
https://www.ncbi.nlm.nih.gov/pubmed/35409271
http://dx.doi.org/10.3390/ijms23073911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999616/
https://www.ncbi.nlm.nih.gov/pubmed/35409271
http://dx.doi.org/10.3390/ijms23073911

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