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Site-Directed Immobilization of an Engineered Bone Morphogenetic Protein 2 (BMP2) Variant to Collagen-Based Microspheres Induces Bone Formation In Vivo

For the treatment of large bone defects, the commonly used technique of autologous bone grafting presents several drawbacks and limitations. With the discovery of the bone-inducing capabilities of bone morphogenetic protein 2 (BMP2), several delivery techniques were developed and translated to clini...

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Detalles Bibliográficos
Autores principales: Siverino, Claudia, Fahmy-Garcia, Shorouk, Mumcuoglu, Didem, Oberwinkler, Heike, Muehlemann, Markus, Mueller, Thomas, Farrell, Eric, van Osch, Gerjo J. V. M., Nickel, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999711/
https://www.ncbi.nlm.nih.gov/pubmed/35409290
http://dx.doi.org/10.3390/ijms23073928