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Lineage Conversion in Pediatric B-Cell Precursor Acute Leukemia under Blinatumomab Therapy

We report incidence and deep molecular characteristics of lineage switch in 182 pediatric patients affected by B-cell precursor acute lymphoblastic leukemia (BCP-ALL), who were treated with blinatumomab. We documented six cases of lineage switch that occurred after or during blinatumomab exposure. T...

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Detalles Bibliográficos
Autores principales: Semchenkova, Alexandra, Mikhailova, Ekaterina, Komkov, Alexander, Gaskova, Marina, Abasov, Ruslan, Matveev, Evgenii, Kazanov, Marat, Mamedov, Ilgar, Shmitko, Anna, Belova, Vera, Miroshnichenkova, Anna, Illarionova, Olga, Olshanskaya, Yulia, Tsaur, Grigory, Verzhbitskaya, Tatiana, Ponomareva, Natalia, Bronin, Gleb, Kondratchik, Konstantin, Fechina, Larisa, Diakonova, Yulia, Vavilova, Liudmila, Myakova, Natalia, Novichkova, Galina, Maschan, Alexey, Maschan, Michael, Zerkalenkova, Elena, Popov, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999738/
https://www.ncbi.nlm.nih.gov/pubmed/35409391
http://dx.doi.org/10.3390/ijms23074019