A Review of the Recent Developments of Molecular Hybrids Targeting Tubulin Polymerization

Microtubules are cylindrical protein polymers formed from αβ-tubulin heterodimers in the cytoplasm of eukaryotic cells. Microtubule disturbance may cause cell cycle arrest in the G2/M phase, and anomalous mitotic spindles will form. Microtubules are an important target for cancer drug action because...

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Detalles Bibliográficos
Autores principales: Ebenezer, Oluwakemi, Shapi, Michael, Tuszynski, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999808/
https://www.ncbi.nlm.nih.gov/pubmed/35409361
http://dx.doi.org/10.3390/ijms23074001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999808/
https://www.ncbi.nlm.nih.gov/pubmed/35409361
http://dx.doi.org/10.3390/ijms23074001

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