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A Review of the Recent Developments of Molecular Hybrids Targeting Tubulin Polymerization
Microtubules are cylindrical protein polymers formed from αβ-tubulin heterodimers in the cytoplasm of eukaryotic cells. Microtubule disturbance may cause cell cycle arrest in the G2/M phase, and anomalous mitotic spindles will form. Microtubules are an important target for cancer drug action because...
Autores principales: | Ebenezer, Oluwakemi, Shapi, Michael, Tuszynski, Jack A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999808/ https://www.ncbi.nlm.nih.gov/pubmed/35409361 http://dx.doi.org/10.3390/ijms23074001 |
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