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Trimethylamine N-Oxide (TMAO) Impairs Purinergic Induced Intracellular Calcium Increase and Nitric Oxide Release in Endothelial Cells

Trimethylamine N-oxide (TMAO) is a diet derived compound directly introduced through foodstuff, or endogenously synthesized from its precursors, primarily choline, L-carnitine, and ergothioneine. New evidence outlines high TMAO plasma concentrations in patients with overt cardiovascular disease, but...

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Detalles Bibliográficos
Autores principales: Querio, Giulia, Antoniotti, Susanna, Geddo, Federica, Levi, Renzo, Gallo, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999849/
https://www.ncbi.nlm.nih.gov/pubmed/35409341
http://dx.doi.org/10.3390/ijms23073982