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Hyperosmotic Stress Induces Phosphorylation of CERT and Enhances Its Tethering throughout the Endoplasmic Reticulum

The ceramide transport protein (CERT) delivers ceramide from the endoplasmic reticulum (ER) to the Golgi apparatus, where ceramide is converted to sphingomyelin (SM). The function of CERT is regulated in two distinct phosphorylation-dependent events: multiple phosphorylations in a serine-repeat moti...

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Detalles Bibliográficos
Autores principales: Shimasaki, Kentaro, Kumagai, Keigo, Sakai, Shota, Yamaji, Toshiyuki, Hanada, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999913/
https://www.ncbi.nlm.nih.gov/pubmed/35409383
http://dx.doi.org/10.3390/ijms23074025