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Hyperosmotic Stress Induces Phosphorylation of CERT and Enhances Its Tethering throughout the Endoplasmic Reticulum
The ceramide transport protein (CERT) delivers ceramide from the endoplasmic reticulum (ER) to the Golgi apparatus, where ceramide is converted to sphingomyelin (SM). The function of CERT is regulated in two distinct phosphorylation-dependent events: multiple phosphorylations in a serine-repeat moti...
Autores principales: | Shimasaki, Kentaro, Kumagai, Keigo, Sakai, Shota, Yamaji, Toshiyuki, Hanada, Kentaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999913/ https://www.ncbi.nlm.nih.gov/pubmed/35409383 http://dx.doi.org/10.3390/ijms23074025 |
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