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Direct Reprogramming and Induction of Human Dermal Fibroblasts to Differentiate into iPS-Derived Nucleus Pulposus-like Cells in 3D Culture

Intervertebral disc (IVD) diseases are common spinal disorders that cause neck or back pain in the presence or absence of an underlying neurological disorder. IVD diseases develop on the basis of degeneration, and there are no established treatments for degeneration. IVD diseases may therefore repre...

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Detalles Bibliográficos
Autores principales: Seki, Shoji, Iwasaki, Mami, Makino, Hiroto, Yahara, Yasuhito, Miyazaki, Yoshitaka, Kamei, Katsuhiko, Futakawa, Hayato, Nogami, Makiko, Tran Canh Tung, Nguyen, Hirokawa, Tatsuro, Tsuji, Mamiko, Kawaguchi, Yoshiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999916/
https://www.ncbi.nlm.nih.gov/pubmed/35409417
http://dx.doi.org/10.3390/ijms23074059