Structure–Activity Relationship of Synthetic Ginkgolic Acid Analogs for Treating Type 2 Diabetes by PTPN9 Inhibition

Ginkgolic acid (C13:0) (GA), isolated from Ginkgo biloba, is a potential therapeutic agent for type 2 diabetes. A series of GA analogs were designed and synthesized for the evaluation of their structure–activity relationship with respect to their antidiabetic effects. Unlike GA, the synthetic analog...

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Detalles Bibliográficos
Autores principales: Kim, Jinsoo, Son, Jinyoung, Ahn, Dohee, Nam, Gibeom, Zhao, Xiaodi, Park, Hyuna, Jeong, Woojoo, Chung, Sang J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999917/
https://www.ncbi.nlm.nih.gov/pubmed/35409287
http://dx.doi.org/10.3390/ijms23073927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999917/
https://www.ncbi.nlm.nih.gov/pubmed/35409287
http://dx.doi.org/10.3390/ijms23073927

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