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Impaired Terminal Erythroid Maturation in β(0)-Thalassemia/HbE Patients with Different Clinical Severity
Anemia in β-thalassemia is associated with ineffective erythropoiesis and a shortened lifespan of erythroid cells. The limited differentiation of β-thalassemic erythroblasts has been documented, but the characteristic feature of terminal erythroid maturation and its physiological relevance are not c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8999960/ https://www.ncbi.nlm.nih.gov/pubmed/35407362 http://dx.doi.org/10.3390/jcm11071755 |