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Hypermethylation-Mediated Silencing of CIDEA, MAL and PCDH17 Tumour Suppressor Genes in Canine DLBCL: From Multi-Omics Analyses to Mechanistic Studies

Gene expression is controlled by epigenetic deregulation, a hallmark of cancer. The DNA methylome of canine diffuse large B-cell lymphoma (cDLBCL), the most frequent malignancy of B-lymphocytes in dog, has recently been investigated, suggesting that aberrant hypermethylation of CpG loci is associate...

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Detalles Bibliográficos
Autores principales: Zorzan, Eleonora, Elgendy, Ramy, Guerra, Giorgia, Da Ros, Silvia, Gelain, Maria Elena, Bonsembiante, Federico, Garaffo, Giulia, Vitale, Nicoletta, Piva, Roberto, Marconato, Laura, Aresu, Luca, Dacasto, Mauro, Giantin, Mery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000013/
https://www.ncbi.nlm.nih.gov/pubmed/35409379
http://dx.doi.org/10.3390/ijms23074021