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Cruciform DNA Structures Act as Legible Templates for Accelerating Homologous Recombination in Transgenic Animals

Inverted repeat (IR) DNA sequences compose cruciform structures. Some genetic disorders are the result of genome inversion or translocation by cruciform DNA structures. The present study examined whether exogenous DNA integration into the chromosomes of transgenic animals was related to cruciform DN...

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Detalles Bibliográficos
Autores principales: Ou-Yang, Huan, Yang, Shiao-Hsuan, Chen, Wei, Yang, Shang-Hsun, Cidem, Abdulkadir, Sung, Li-Ying, Chen, Chuan-Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000021/
https://www.ncbi.nlm.nih.gov/pubmed/35409332
http://dx.doi.org/10.3390/ijms23073973