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Ribavirin for treating Lassa fever: A systematic review of pre-clinical studies and implications for human dosing

Ribavirin is currently the standard of care for treating Lassa fever. However, the human clinical trial data supporting its use suffer from several serious flaws that render the results and conclusions unreliable. We performed a systematic review of available pre-clinical data and human pharmacokine...

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Detalles Bibliográficos
Autores principales: Salam, Alex P., Duvignaud, Alexandre, Jaspard, Marie, Malvy, Denis, Carroll, Miles, Tarning, Joel, Olliaro, Piero L., Horby, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000057/
https://www.ncbi.nlm.nih.gov/pubmed/35353804
http://dx.doi.org/10.1371/journal.pntd.0010289