Aggregation chimeras provide evidence of in vivo intercellular correction in ovine CLN6 neuronal ceroid lipofuscinosis (Batten disease)

The neuronal ceroid lipofuscinoses (NCLs; Batten disease) are fatal, mainly childhood, inherited neurodegenerative lysosomal storage diseases. Sheep affected with a CLN6 form display progressive regionally defined glial activation and subsequent neurodegeneration, indicating that neuroinflammation m...

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Detalles Bibliográficos
Autores principales: Barry, Lucy Anne, Kay, Graham William, Mitchell, Nadia Lesley, Murray, Samantha Jane, Jay, Nigel P., Palmer, David Norris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000108/
https://www.ncbi.nlm.nih.gov/pubmed/35404973
http://dx.doi.org/10.1371/journal.pone.0261544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000108/
https://www.ncbi.nlm.nih.gov/pubmed/35404973
http://dx.doi.org/10.1371/journal.pone.0261544

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