IGFBP-3 Regulates Mitochondrial Hyperfusion and Metabolic Activity in Ocular Surface Epithelia during Hyperosmolar Stress

In the eye, hyperosmolarity of the precorneal tear film triggers inflammation and the development of dry eye disease (DED), a highly prevalent condition that causes depression and disability in severe forms. A member of the insulin-like growth factor (IGF) family, the IGF binding protein-3 (IGFBP-3)...

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Detalles Bibliográficos
Autores principales: Stuard, Whitney L., Guner, Melis K., Robertson, Danielle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000157/
https://www.ncbi.nlm.nih.gov/pubmed/35409425
http://dx.doi.org/10.3390/ijms23074066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000157/
https://www.ncbi.nlm.nih.gov/pubmed/35409425
http://dx.doi.org/10.3390/ijms23074066

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