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Rhein Improves Renal Fibrosis by Restoring Cpt1a-Mediated Fatty Acid Oxidation through SirT1/STAT3/twist1 Pathway

The latest progress in the field of renal fibrosis mainly focuses on the new concept of “partial epithelial-mesenchymal transition (pEMT)” to explain the contribution of renal tubular epithelial (RTE) cells to renal fibrosis and the crucial role of fatty acid oxidation (FAO) dysfunction in RTE cells...

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Detalles Bibliográficos
Autores principales: Song, Xianrui, Du, Zesen, Yao, Zhenqi, Tang, Xiaoyan, Zhang, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000220/
https://www.ncbi.nlm.nih.gov/pubmed/35408745
http://dx.doi.org/10.3390/molecules27072344