Non-Peptide Opioids Differ in Effects on Mu-Opioid (MOP) and Serotonin 1A (5-HT(1A)) Receptors Heterodimerization and Cellular Effectors (Ca(2+), ERK1/2 and p38) Activation

The importance of the dynamic interplay between the opioid and the serotonin neuromodulatory systems in chronic pain is well recognized. In this study, we investigated whether these two signalling pathways can be integrated at the single-cell level via direct interactions between the mu-opioid (MOP)...

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Detalles Bibliográficos
Autores principales: Radoi, Vlad, Jakobsson, Gerd, Palada, Vinko, Nikosjkov, Andrej, Druid, Henrik, Terenius, Lars, Kosek, Eva, Vukojević, Vladana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000251/
https://www.ncbi.nlm.nih.gov/pubmed/35408749
http://dx.doi.org/10.3390/molecules27072350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000251/
https://www.ncbi.nlm.nih.gov/pubmed/35408749
http://dx.doi.org/10.3390/molecules27072350

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