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Fungus-Derived 3-Hydroxyterphenyllin and Candidusin A Ameliorate Palmitic Acid-Induced Human Podocyte Injury via Anti-Oxidative and Anti-Apoptotic Mechanisms

Diabetic nephropathy (DN) is a leading cause of end-stage renal disease. An elevated fatty acid plasma concentration leads to podocyte injury and DN progression. This study aimed to identify and characterize cellular mechanisms of natural compounds that inhibit palmitic acid (PA)–induced human podoc...

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Detalles Bibliográficos
Autores principales: Kaewin, Suchada, Changsorn, Karn, Sungkaworn, Titiwat, Hiranmartsuwan, Peraya, Yaosanit, Wiriya, Rukachaisirikul, Vatcharin, Muanprasat, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000303/
https://www.ncbi.nlm.nih.gov/pubmed/35408508
http://dx.doi.org/10.3390/molecules27072109