Development of Bicyclo[3.1.0]hexane-Based A(3) Receptor Ligands: Closing the Gaps in the Structure–Affinity Relationships

The adenosine A(3) receptor is a promising target for treating and diagnosing inflammation and cancer. In this paper, a series of bicyclo[3.1.0]hexane-based nucleosides was synthesized and evaluated for their P1 receptor affinities in radioligand binding studies. The study focused on modifications a...

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Detalles Bibliográficos
Autores principales: Lemmerhirt, Jan Phillip, Isaak, Andreas, Liu, Rongfang, Kock, Max, Daniliuc, Constantin G., Jacobson, Kenneth A., Heitman, Laura H., Junker, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000336/
https://www.ncbi.nlm.nih.gov/pubmed/35408685
http://dx.doi.org/10.3390/molecules27072283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000336/
https://www.ncbi.nlm.nih.gov/pubmed/35408685
http://dx.doi.org/10.3390/molecules27072283

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