Microwave-Assisted Synthesis, Biological Activity Evaluation, Molecular Docking, and ADMET Studies of Some Novel Pyrrolo [2,3-b] Pyrrole Derivatives

Novel pyrrolo [2,3-b] pyrrole derivatives were synthesized and their hypolipidemic activity was assessed in hyperlipidemic rats. The chemical structures of the new derivatives were confirmed through spectral analysis. Compounds 5 and 6 were revealed to be the most effective hypolipidemic agents, wit...

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Detalles Bibliográficos
Autores principales: Kamel, Moumen S., Belal, Amany, Aboelez, Moustafa O., Shokr, E. Kh., Abdel-Ghany, H., Mansour, Hany S., Shawky, Ahmed M., El-Remaily, Mahmoud Abd El Aleem Ali Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000376/
https://www.ncbi.nlm.nih.gov/pubmed/35408463
http://dx.doi.org/10.3390/molecules27072061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000376/
https://www.ncbi.nlm.nih.gov/pubmed/35408463
http://dx.doi.org/10.3390/molecules27072061

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