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Design, Synthesis, and Evaluation of Novel 2H-Benzo[b][1,4]thiazin-3(4H)-one Derivatives as New Acetylcholinesterase Inhibitors

Alzheimer’s disease (AD) is a slowly progressive neurodegenerative disease that causes dementia in people aged 65 and over. In the present study, a series of thiadiazole hybrid compounds with benzothiazine derivatives as acetylcholinesterase inhibitors were developed and evaluated for their biologic...

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Detalles Bibliográficos
Autores principales: Haji Ali, Sazan, Osmaniye, Derya, Sağlık, Begüm Nurpelin, Levent, Serkan, Özkay, Yusuf, Kaplancıklı, Zafer Asım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000418/
https://www.ncbi.nlm.nih.gov/pubmed/35408519
http://dx.doi.org/10.3390/molecules27072121